That sudden itch, the watery eyes, the sneezing fit – allergies are the worst! If you've reached for Benadryl (diphenhydramine), you're probably wondering, "How long does it take for Benadryl to work?"
Good news: Benadryl usually starts working within **15 to 30 minutes** after taking it orally. You'll likely notice a reduction in your allergy symptoms like itching, sneezing, and runny nose within that timeframe. Peak effectiveness is generally reached in about 1 to 2 hours.
Keep in mind that factors like your metabolism, how much you've eaten, and the severity of your allergies can influence how quickly Benadryl takes effect. Also, remember that Benadryl can cause drowsiness, so avoid operating heavy machinery or driving until you know how it affects you. If your symptoms don't improve after an hour, or if they worsen, consult with your doctor or a healthcare professional.