Ever wondered 'how GHB works' and its effects on the human body? GHB (gamma-hydroxybutyrate) is a central nervous system depressant that's gained notoriety for both medical and recreational uses, as well as its association with drug-facilitated sexual assault.
GHB primarily works by binding to two receptors in the brain: the GHB receptor and the GABA-B receptor. Binding to the GHB receptor is believed to be responsible for the cognitive and mood-altering effects at lower doses. At higher concentrations, GHB primarily activates the GABA-B receptor, leading to more pronounced sedative and depressant effects.
These interactions result in a range of effects, from feelings of euphoria and relaxation to drowsiness, dizziness, and even loss of consciousness. The effects are highly dose-dependent and vary greatly between individuals, making GHB particularly dangerous. Overdoses can cause seizures, coma, and respiratory depression.
It's crucial to understand the risks associated with GHB use. If you or someone you know is struggling with substance abuse, please seek professional help.
